BPC-157
BPC-157 is a synthetic pentadecapeptide derived from a partial sequence of the body protection compound (BPC) found in gastric juice. In vitro and ex vivo studies investigate its potential to influence angiogenesis, modulate growth factor expression, and support fibroblast migration in models of tissue regeneration. Research also explores its interactions with nitric oxide pathways and its effects on cellular signaling related to inflammatory response.
For laboratory research use only. Not for human or veterinary use. Not intended for diagnostic, therapeutic, or clinical applications.
Purchase Options
BPC-157
Form: Scientific-grade, Lyophilized Powder
Purity: ≥99%
CAS Number: 137525-51-0
BPC-157 is a synthetic pentadecapeptide derived from a partial sequence of body protection compound (BPC). It is studied in non-clinical research for its potential effects on angiogenesis, tissue regeneration, and cellular signaling. Supplied for research use only and not approved for human or veterinary use.
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Chemical Structure & Identifiers
BPC-157 is provided for non-clinical research involving peptide-receptor interactions, angiogenesis models, and tissue regeneration studies. This compound is not approved for therapeutic, diagnostic, or in vivo use.
Clinical Development & Research Focus
BPC-157 has been a subject of extensive **preclinical research** across numerous animal models and continues to be a major **research focus** for its broad regenerative and protective properties. While its potential therapeutic applications are wide-ranging, formal, large-scale human clinical trials are limited or ongoing, primarily in specific areas.
- Tissue and Organ Repair: Primary research extensively investigates its ability to accelerate the healing of various tissues, including muscles, tendons, ligaments, bones, and even nerve tissue, in animal models of injury and disease.
- Gastrointestinal Protection: Significant focus is placed on its cytoprotective effects on the gastrointestinal tract, including the healing of ulcers (gastric, duodenal), inflammatory bowel disease models, and protection against NSAID-induced damage.
- Systemic Healing and Anti-inflammatory Effects: Studies explore its systemic benefits in models of various inflammatory conditions, vascular injuries, and multi-organ damage, often demonstrating a rapid and robust healing response.
- Neurological Recovery: Emerging research investigates its neuroprotective properties and potential for promoting recovery in models of brain and spinal cord injury, including effects on neurotransmitter systems.
- Vascular Health and Angiogenesis: Research consistently highlights its pro-angiogenic properties and ability to improve blood vessel integrity and function, which is critical for tissue repair.
It is important to note that while preclinical evidence is strong and diverse, BPC-157 remains an **investigational research chemical**. Its use outside of controlled research settings is not approved by regulatory bodies for any therapeutic use in humans or animals.
Guidelines for Experimental Use
BPC-157 is strictly intended for **laboratory research purposes only**. It must be handled by qualified research personnel in a controlled laboratory environment, adhering to all applicable safety protocols and guidelines for investigational research chemicals. This product is **not approved for human consumption, therapeutic use, or veterinary applications**. Its use is limited to scientific investigation and analysis. Proper laboratory safety equipment, including personal protective equipment (PPE), and procedures must be employed during its handling, storage, and experimental application. Researchers should consult relevant safety data sheets (SDS) and institutional guidelines before use.
Key Scientific References
For more detailed information on BPC-157 and its research applications, please refer to the following scientific literature and review articles, primarily from preclinical studies:
- Lojo N et al. BPC 157 and multi-organ lesions in short-bowel rats. PLoS One, 2016. PMID: 27627764
- Djakovic Z et al. Esophagogastric anastomosis healing with BPC 157. World J Gastroenterol, 2016. PMID: 27895400
- Drmic D et al. BPC 157 in perforated cecum lesions. World J Gastroenterol, 2018. PMID: 30622376
- Sikiric P et al. NSAID toxicity counteraction. Curr Pharm Des, 2013. PMID: 22950504
- Sikiric P et al. Stress and BPC 157 in GI tract. Curr Pharm Des, 2017. PMID: 28228068
- Knezevic M et al. Superior mesenteric vein occlusion. Biomedicines, 2021. PMID: 34440233
- He L et al. Pharmacokinetics of BPC 157 in animals. Front Pharmacol, 2022. PMID: 36588717
- PubChem Compound Summary: BPC-157 (CID 9941957)
*(Note: References are primarily focused on preclinical and mechanistic studies, reflecting BPC-157's status as a research compound.)*
Important Compliance Statement
This product, BPC-157, is sold exclusively for **research and development purposes**. It is classified as a research chemical and is **not a drug, food, or cosmetic**. It has not been evaluated or approved by the FDA or any other regulatory authority for safety, efficacy, or any other use in humans or animals. By purchasing this product, the user acknowledges and agrees to comply with all applicable local, national, and international laws and regulations regarding the handling, storage, and use of research compounds. Any use of this product for purposes other than legitimate scientific research is strictly prohibited and may lead to severe legal and health consequences.
Analytical Validation & Documentation (COA, HPLC, MS)
Each production lot is subjected to rigorous analytical validation to confirm quality, purity, and molecular identity under research-grade standards. Full supporting documentation is available upon request.
- COA (Certificate of Analysis): Includes batch number, purity percentage, traceability of each constituent ingredient, storage instructions, and full QC test results.
- HPLC (High-Performance Liquid Chromatography): Provides chromatographic confirmation of purity and compound homogeneity.
- MS (Mass Spectrometry): Confirms molecular weight and verifies structural integrity of the compound.
- Traceability: Documents are traceable to their respective manufacturing lot and are intended to support reproducibility and transparency in scientific investigation.
Displayed above: Sample Certificate of Analysis – AOD-9604 (3-page image preview)
Storage & Shipping
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures stability during transit and long-term storage. Below are the official recommendations:
- Stability During Shipping: Products are 100% stable for shipping for up to 3–4 months at ambient temperature.
- After Reconstitution: Once reconstituted with bacteriostatic water, the peptide must be stored in a refrigerator and will remain stable for up to 30 days.
- Room Temperature Storage: Lyophilized powder can be safely stored at room temperature until reconstitution, provided it remains sealed and protected from light.
- Refrigerated Storage (Short Term): Store under 4°C (39°F) if not used immediately. Suitable for storage up to several weeks or months.
- Frozen Storage (Long Term): For extended stability (months to years), store in a freezer at -80°C (-112°F).
Note: Avoid repeated freeze-thaw cycles. Always aliquot after reconstitution when necessary. Follow institutional safety protocols for handling all research compounds.
For advanced storage tips and reconstitution guidance, contact us or refer to our extended documentation.