GHK-Cu

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper complex) is a widely studied copper-binding peptide found naturally in human plasma. In **preclinical research**, it has demonstrated various biological activities relevant to tissue regeneration and repair:

• Wound Healing: GHK-Cu has been shown to promote wound healing by stimulating collagen synthesis, angiogenesis, and antioxidant enzyme activity.
• Anti-Aging & Skin Health: Research indicates its potential in skin rejuvenation by improving elasticity, reducing wrinkles, and protecting against oxidative damage. It's thought to stimulate dermal fibroblast proliferation and modulate collagen and elastin production.
• Anti-inflammatory Effects: Studies suggest GHK-Cu possesses anti-inflammatory properties by modulating various inflammatory pathways and reducing oxidative stress.
• Hair Growth: Some preclinical studies explore its role in stimulating hair follicle growth and preventing hair loss.
• Neuroprotection: Emerging research investigates its potential neuroprotective effects and role in central nervous system repair.

Its broad regenerative and protective properties make GHK-Cu a significant focus in dermatological, anti-aging, and regenerative medicine research.

GHK-Cu is strictly intended for **laboratory research purposes only**. It must be handled by qualified research personnel in a controlled laboratory environment, adhering to all applicable safety protocols and guidelines for investigational research chemicals. This product is **not approved for human consumption, therapeutic use, or veterinary applications**. Its use is limited to scientific investigation and analysis. Proper laboratory safety equipment, including personal protective equipment (PPE), and procedures must be employed during its handling, storage, and experimental application. Researchers should consult relevant safety data sheets (SDS) and institutional guidelines before use.

For optimal stability and preservation of GHK-Cu, observe the following recommendations:

• Storage: Store lyophilized powder at -20°C to -80°C (long-term) or 2°C to 8°C (short-term, for up to 2-4 weeks), away from light and moisture.
• Reconstitution: Reconstitute with sterile, deionized water or a suitable solvent as per specific experimental protocols. Avoid repeated freeze-thaw cycles.
• Manejo Handle under aseptic conditions to prevent contamination. Use appropriate personal protective equipment (PPE), including gloves and eye protection. Copper peptides can stain, so care should be taken.
• Stability: Once reconstituted, solutions should be stored at 2°C to 8°C and used within a short period, typically 24-72 hours, depending on the solvent and concentration. Long-term storage of reconstituted solutions is not recommended.
• Disposal: Dispose of GHK-Cu and any waste materials in accordance with local and institutional hazardous waste regulations.

Strict adherence to these guidelines will help maintain the integrity and purity of the compound for research applications.

For more detailed information on GHK-Cu and its research applications, please refer to the following scientific literature and review articles, primarily from preclinical studies:

• Pickart L, Vasquez-Soltero JM, Margolina A. GHK and DNA Repair. J Am Acad Dermatol, 2012. PMID: 22644163
• Pickart L, Vasquez-Soltero JM, Margolina A. GHK-Cu in anti-aging. Aging Res Rev, 2012. PMID: 22153215
• Gorouhi F, Maibach HI. Topical peptides in dermatology. J Drugs Dermatol, 2010. PMID: 20516568
• Fukayama M, et al. Effects of copper peptide GHK-Cu on skin. J Cosmet Dermatol, 2015. PMID: 25553147
• Han M, et al. Anti-aging effects of copper peptide GHK-Cu. Pharmaceuticals (Basel), 2021. PMID: 33849044
• PubChem Compound Summary: GHK-Cu (CID 9831891)

*(Note: References are primarily focused on preclinical and mechanistic studies, reflecting GHK-Cu's status as a research compound.)*

This product, GHK-Cu, is sold exclusively for **research and development purposes**. It is classified as a research chemical and is **not a drug, food, or cosmetic**. It has not been evaluated or approved by the FDA or any other regulatory authority for safety, efficacy, or any other use in humans or animals. By purchasing this product, the user acknowledges and agrees to comply with all applicable local, national, and international laws and regulations regarding the handling, storage, and use of research compounds. Any use of this product for purposes other than legitimate scientific research is strictly prohibited and may lead to severe legal and health consequences.