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Acetyl Decapeptide-3

Research Peptide Compound – For Laboratory Use Only

Acetyl Decapeptide-3 Acetyl Decapeptide-3 is examined in vitro for modulation of fibroblast signaling, including upregulation of growth factors and ECM proteins such as collagen and fibronectin. Research focuses on pathways implicated in tissue regeneration and structural protein homeostasis.

For laboratory research use only. Not for human or veterinary use. Not intended for diagnostic, therapeutic, or clinical applications.

Purchase Options

Acetyl Decapeptide-3

Grade: Scientific

Form: Freeze Dried - Lyophilized Powder

Container: Liquid Nitrogen Filled Cryogenic Vial

Purity: ≥99%

CAS Number: 935288-50-9

Acetyl Decapeptide-3 is a synthetic peptide under investigation for its potential applications in skin and cellular signaling research.

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Chemical Structure & Identifiers

INCI Name: Acetyl Decapeptide-3 Synonyms: Rejuline, HY-P3047, DA-60720 CAS Number: 935288-50-9 UNII Code: 30510A08G7 PubChem CID: 91936932 Sequence: Ac-Tyr-Arg-Ser-Arg-Lys-Tyr-Thr-Ser-Trp-Tyr-NH2 Molecular Formula: C56H94N16O16S Molecular Weight: 1299.6 g/mol (approximate)
Structure of Acetyl Decapeptide-3

Scientific Research Overview

This section outlines the mechanistic insights, research background, experimental guidance, supporting literature, and compliance statements for Acetyl Decapeptide-3.

Mechanism of Action

Acetyl Decapeptide-3 is a synthetic decapeptide (a peptide composed of 10 amino acids) that is primarily investigated in cosmetic and biochemical research for its potential role in influencing cellular processes related to skin health and regeneration. Its mechanism of action is thought to involve interactions with specific cellular receptors and signaling pathways.

  • Signaling Molecule Activity: The peptide is believed to act as a signaling molecule, mimicking naturally occurring peptides that regulate cell proliferation, migration, and extracellular matrix (ECM) production. This can lead to improved cellular function.
  • Fibroblast Stimulation (Proposed): Research suggests it may stimulate fibroblasts, the cells responsible for synthesizing collagen, elastin, and hyaluronic acid. By enhancing the activity of these cells, Acetyl Decapeptide-3 aims to promote skin firmness, elasticity, and hydration.
  • Antioxidant and Anti-Inflammatory Effects (Emerging Research): While less defined, some studies explore its potential to offer mild antioxidant protection by reducing oxidative stress, and anti-inflammatory properties by modulating inflammatory cytokine production.

Its complex structure allows for potential interactions with various cellular components, positioning it as a versatile tool for researchers studying skin biology and peptide therapeutics.

Clinical Development & Research Focus

Acetyl Decapeptide-3 is a subject of **preclinical and cosmetic research**, with studies primarily focusing on its application in dermatological and anti-aging contexts. It has been explored for its potential to improve various skin parameters.

  • Skin Rejuvenation: Research evaluates its efficacy in reducing the appearance of fine lines and wrinkles, improving skin texture, and enhancing overall skin vitality.
  • Collagen and Elastin Production: Studies investigate its ability to upregulate the synthesis of key extracellular matrix proteins like collagen and elastin, which contribute to skin firmness and elasticity.
  • Cell Proliferation and Migration: Laboratory experiments examine its impact on the proliferation and migration of skin cells (e.g., keratinocytes, fibroblasts), essential for wound healing and tissue repair.
  • Formulation Stability and Delivery: Research also focuses on optimizing the stability of Acetyl Decapeptide-3 in topical formulations and developing efficient delivery systems to ensure its bioavailability in skin layers.

While often found in advanced cosmetic formulations, it's important to note that its "clinical development" is typically conducted within the cosmetic industry to support product claims, differing from the rigorous pharmaceutical drug approval processes. It remains a research chemical for laboratory purposes.

Guidelines for Experimental Use

Acetyl Decapeptide-3 is strictly intended for **laboratory research purposes only**. It must be handled by qualified research personnel in a controlled laboratory environment, adhering to all applicable safety protocols and guidelines for investigational research chemicals. This product is **not approved for human consumption, therapeutic use, or veterinary applications**. Its use is limited to scientific investigation and analysis. Proper laboratory safety equipment, including personal protective equipment (PPE), and procedures must be employed during its handling, storage, and experimental application. Researchers should consult relevant safety data sheets (SDS) and institutional guidelines before use.

Key Scientific References

For more detailed information on **Acetyl Decapeptide-3** and its research applications, please refer to the following scientific literature and related reviews:

*(Note: Direct, independent peer-reviewed publications specifically on "Acetyl Decapeptide-3" by its generic name may be limited as it is often part of proprietary formulations. General peptide research and reviews provide broader scientific context.)*

Important Compliance Statement

This product, **Acetyl Decapeptide-3**, is sold exclusively for **research and development purposes**. It is classified as a research chemical and is **not a drug, food, or cosmetic**. It has not been evaluated or approved by the FDA or any other regulatory authority for safety, efficacy, or any other use in humans or animals. By purchasing this product, the user acknowledges and agrees to comply with all applicable local, national, and international laws and regulations regarding the handling, storage, and use of research compounds. Any use of this product for purposes other than legitimate scientific research is strictly prohibited and may lead to severe legal and health consequences.

Analytical Validation & Documentation (COA, HPLC, MS)

Each batch of Acetyl Decapeptide-3 undergoes rigorous analytical validation to ensure quality, purity, and identity in accordance with research-grade standards. Detailed documentation is available both digitally and in hard copy upon request.

  • COA (Certificate of Analysis): Includes batch number, purity percentage, traceability of each constituent ingredient, storage instructions, and full QC test results.
  • HPLC (High-Performance Liquid Chromatography): Provides chromatographic confirmation of purity and compound homogeneity.
  • MS (Mass Spectrometry): Confirms molecular weight and verifies structural integrity of the compound.
COA Page 1 COA Page 2 COA Page 3

Displayed above: Sample Certificate of Analysis – AOD-9604 (3-page image preview)

Storage & Shipping

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures stability during transit and long-term storage. Below are the official recommendations:

  • Stability During Shipping: Products are 100% stable for shipping for up to 3–4 months at ambient temperature.
  • After Reconstitution: Once reconstituted with bacteriostatic water, the peptide must be stored in a refrigerator and will remain stable for up to 30 days.
  • Room Temperature Storage: Lyophilized powder can be safely stored at room temperature until reconstitution, provided it remains sealed and protected from light.
  • Refrigerated Storage (Short Term): Store under 4°C (39°F) if not used immediately. Suitable for storage up to several weeks or months.
  • Frozen Storage (Long Term): For extended stability (months to years), store in a freezer at -80°C (-112°F).

Note: Avoid repeated freeze-thaw cycles. Always aliquot after reconstitution when necessary. Follow institutional safety protocols for handling all research compounds.

For advanced storage tips and reconstitution guidance, contact us or refer to our extended documentation.

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